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Jimmy Scott Elkinsto a major auction house, it had a stain on the reverse (as seen in Lipset's Encyclopedia). The President of the company called and asked me if it was OK for them to have the stain removed. After a few seconds of thought, I said OK (because I was getting out of the Hobby and knew the card would bring more money in EX than in GD). Anyway, if I hadn't known the stain was once there, I would have never guessed the card ever had a stain after viewing the "after" picture in the catalog.
Personally, my opinion is: "removal of something not originally on the card is not taboo". When one starts adding colors, corners (paper), etc.; that is a "no-no".