Will you get vaccinated against COVID once it's available?

[Peter_Spaeth]

Originally Posted by G1911

I'll even assume that this is true and it is now impossible to use controls. Does it not still suggest that the earlier studies are better, because they use controls? Why should I ignore the science before March, 2020 and just accept whatever the CDC says after March 2020?

See my addendum quoting what they said about RCTs. And I am relying at the moment on this article, not the CDC.

I'll repeat the quote so it's in one place with your question.

"The standard RCT paradigm is well suited to medical interventions in which a treatment has a measurable effect at the individual level and, furthermore, interventions and their outcomes are independent across persons comprising a target population.

By contrast, the effect of masks on a pandemic is a population-level outcome where individual-level interventions have an aggregate effect on their community as a system."