If they're under there for years there will probably be some damage. Usually keeping the card from touching the glass is a good idea.
Light will be a problem. A few years will definetly cause fading. In a frame there are a few types of UV blocking glass, but I don't think those would hold up well on a desk.
Maybe a piece of thin Uv blocking plastic, an acid free mat with cutouts for each one, and a layer of acid free paper? That could work, and would allow a creative layout for the display.
If you can't stand looking at the empty spaces you could always pick up a set of reprints and replace them with real ones as you get them.
Steve B
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