I think to answer the question properly, you would need to assess what's in the collection. If it's all slabbed vintage cards, it's very liquid with a deep market so putting it in an auction would work just fine. I've been selling mine over the years and because it consisted of more esoteric memorabilia it was a little tricky. What I discovered is if you're patient, you will eventually find a collector who will pay a good price for at least some of it. Some pieces that I couldn't find buyers for went to auction, with very mixed results. Some did well, and some tanked. So in this environment I would be careful if you have something that may not be all that popular. I guess one's urgency plays a factor too- is it a long term project or do you need the money for something pressing? Overall I would say a good strategy, carefully thought out, is the best one can do in this economy. Don't expect miracles unless all you have are T206 rare backs.
