if you want to include scans, I believe "Bento" would be a good product for your needs. Its basically filemaker with all of the database programming work done for you with a bunch of pre-done templates.
http://www.filemaker.com/products/be...bento_overview
If it was my collection - I would rather just create a simple spreadsheet. Include the issue, year, name of player, variation, condition, maybe purchase price, purchase date, sold price, sold date.
I would keep my scans somewhere else / like iPhoto / or in a personal photobucket site.
Bobby's VCP suggestion is a nice one - but I would guess you would want to control that information on your own computer (I would).... I would go with Bento or a spreadsheet.