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Craig WI think the most affordable T206 back subset might be the Piedmont 350-460 Factory 25 (not Factory 42). I believe there are "only" 110 different fronts associated with this back, and it doesn't sell for any premium to speak of. As for the stars/HOFer's, there's of course the six superprints, as well as Cobb Bat Off, a Brown, a Chance, a Tinker off the top of my head. I don't think there are any rarities. Perhaps Ted, Scot, Brian W or someone can chime in.
Edit to add: Baker, Johnson, LaJoie, Wheat, Young Glove, a couple McGraws, Gandil, Smith Chi & Bos ... so maybe it's not the most affordable.