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JimBRegistry would be a factor for me. If my cards were high grade and there was a strong competition for high grade cards from my set on one of the registries, i would go for that one. If my cards were mid-grade or low-grade and there were more registry people at those levels on another registry, I would go for that one. A lot of set collectors try to complete set in all one type of holder, so I would aim towards the biggest market in the appropriate holder for your anticipated grades.
JimB