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Posted By: Pennsylvania Ted

There are theoretically 144 cards in the T206 set that were issued 1st with the 150 Series in 1909, and
then again with the 2nd Series in 1910 having 350 backs.

I say "theoretically", because this rule varies, depending on the Tobacco brand on the back of the T206's.

In the majority of the cases, the value of a given T206 does not change whether it has a 150 or a 350 back.