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BrianGAI is much more reasonable, I believe, when it comes to glue residue on the back.I speak from experience as I just ran into this issue. So if you have a Vg-Ex front but glue residue/small amount of paper loss on back, it would probably grade a 2-2.5. It depends to some extent on the area that is covered by the defect. They put more emphasis on eye appeal, which is the way it should be, in my humble opinion.
I don't get this widespread concept of uniformity within grading companies--mentioned many times on this forum--that is buying the holder, not the card. If you really like a card, buy the card, irrespective of the holder.