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AnsonDavid is right.  Sometimes the hardest flaw to spot is a wrinkle.  And, these wrinkles will immediately drop the grade to a 5 (at the very best).  Other, not-so-obvious flaws that will dramatically affect an otherwise nice looking card are: tiny bits of paper loss, erased pencil marks, chipping, etc.  Some of these aren't very obvious but will still drop your card down to the PSA 1-2 range.