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JJThe purist would want you to keep the sheet intact, but if you are going to grade and trade/sell then you want to cut. I have cut up a 1957, 1960 and a 1962 Topps sheet. My profit from these cards was 5 fold from the orginal price that I paid for the sheets. This included the grading and the cutting. I did this to fuel my vintage card buying. I would not do this to a real vintage sheet but it was only a couple of Topps sheets.