Interesting topic, especially for those who are having fun. Here's my shot:
C- Johnny Bench
P- Bob Gibson
1B- Lou Gehrig
2B- Rod Carew
SS- Honus Wagner
3B- Jim Thome (he started as a 3B and his offensive stat line is outstanding)
OF- Hank Aaron
OF- Ted Williams
OF- Roberto Clemente
DH- Babe Ruth
Relief- Sandy Koufax (just to get him in there after 8 innings of the Hoot)
Manager- doesn't really matter, since he can't screw up this lineup
Hard to leave out- Rickey Henderson, Mantle (runner up DH)
Trent King