My favorites are generally the ones I have an illogical fond memory of collecting when I first started with my father. My T205 Livingston that was my first T card, my T205 Knight (Portrait) that was my first T206, my T3 Admiral Schlei that was my first cabinet, the E94 Lake and Devlin and E98 Vaughn (Red) that I found in Cooperstown, New York for $20 each and my dad bought me. Because of the small budget when I was a kid, none of these cards have much interest or note to anyone else.
This is probably my most precious card item now, not a single card but it was a single sheet. I have 20 of the 25 fragments, 2 of which apparently do not exist anymore 112 years later. The Donovan has only 4 non-proof copies known and was unproven to exist until 2006. I would also sell it for $5,000,000, but have turned down what I would to be consider significant offers for it, since even threads specifically about not-money become about money