I don't know about registry bait type cards, but I know for upper midgrade or even like PSA 7, they sometimes ignore the rules on back centering. I have a '66 Koufax that should have gotten the MC qualifier because of the back - PSA gave it a straight 6. Personally as long as the back is mostly there, I could give a flip about back centering.
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Postwar stars & HOF'ers. Cubs of all eras. Currently working on 1956, '63 and '72 Topps complete sets.
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