In 2019, you could have purchased lots of sweet cards with that kind of money. In today's market, 100k won't get you much - maybe four or five blue chips and that's it. It sucks.
Now, to answer the OP's question, I'd pick a few from this list below:
Baseball
- Leaf Jackie Robinson
- World Wide Gum Co. Joe DiMaggio
- Bowman Willie Mays
- Bowman Mickey Mantle
Football
- National Chicle Bronko Nagurski
- Topps Jim Brown
- Topps Joe Namath
Hockey
- Parkhurst Gordie Howe
- Topps Bobby Orr
- Topps Bobby Hull
Basketball
- Topps Bill Russell
- Fleer Wilt Chamberlain