I too remember many years ago when it was taboo and frowned upon to have a vintage card signed. Was considered "ruining" the card. I think we've seen in recent years, it's actually the opposite, and obviously with players like Ruth, Gehrig, Mantle, (Goudeys, early Topps, etc), they've become very sought after and desirable.
I'm actually selling this example in the current Heritage Platinum Auction...shameless plug.
https://sports.ha.com/itm/baseball-c...ignment-112816