Everyone has their own preferences here, personally I hate qualifiers. Points out/polarizes flaws which are often subjective. I’ve seen cards with centering issues and no qualifiers worse than some marked as “OC“. Last submission to PSA at a trade show, their rep said not a problem to note “no qualifiers” on the submission and they still sent a couple cards back with them

.. I cracked them out and resubmitted to SGC. Again, that’s a personal preference thing and debatable whether or not you’ll see any monetary gain because of it.
Edit to add: Regarding your question about 4MC equaling 2 or 1.5, yes – that’s the general thought (about a two grade bump-down) .. but again, buyer subjective based on his/her own needs/taste