Nothing. I will pay a premium for a heavy miscut, but centering is both a natural defect from the techniques of a century ago, and doesn't really impact a cards visual aesthetics to my eyes. I don't do high grade, but things like registration, brightness, etc. have a much greater impact on how a card looks.
I will take a creased up, pinholed and wildly off center Old Judge with a bright image over a PSA 6 with 50/50 centering that's fading.
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