I generally only collect autographed memorabilia, letters or index cards, but if I were going to collect pieces like this, or especially the ones with odd shapes from slicing around other autographs on a sheet, I would consider getting them slabbed. I like the idea of having them both protected and a uniform size.
But my first thought when acquiring something like your examples, would be to mat and frame them with a nice photograph. In those cases, if you really need the LOA, you can get one that has a photo of the item on it.
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