In addition to the beautiful black background, leaving the lid open in a dark room (all the way dark, not kinda dark) also helps the scan have truer colors and will mean that you frequently don't have to tweak them. Scans where the colors have been edited often don't end up looking anything like they are supposed to.
I also always scan on the highest setting (600 dpi on mine) to get the best possible image. If you need to send/post a bunch of smaller files it is easy to compress and save a copy after the fact, but nobody wants to scan things twice so start with the highest possible resolution.
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