My advice would be to TAKE YOUR TIME!! There is an amazing amount of stuff crammed into that place and you'll miss a lot if you rush..
Another thing to consider is the town itself. There are some great little restaurants and a TON of card/memorabilia shops that are museums in their own right.
If going with a significant other who could care less or is only mildly interested, you may want to do your research about the area and they could drop you off.
If you are a beer drinker, Ommegang Brewery has an amazing "belgian-style" brewery not far away and there is also Cooperstown Brewing company.
Hope this helps.
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