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jeff sfor players like Mantle, who signed so much, we can be sure that his autograph looks like the sharpie one on this card. (now...there are pretty good forgers out there, but many of their techniques are easily recognized)
Also - I don't think that all of the autographs that were used for facsimilies were the player's actual signature. Many are accurate, of course (it's always cool to have an old card with a fac. sig with a real sharpie auto that looks exactly the same), but many facsimilies are either a) not accurate at all, or b) much less "stylish" than the autographs they sign for fans because, perhaps, of space restrictions, or c) their entire name -- "Gordon S. Cochrane" instead of "Mickey Cochrane."
now, that isn't to say that autograph collecting is free of risk......but that's another story.