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Hal LewisAll the "One-of-a-Kind" vintage cards are becoming more and more valuable as people truly seek out rarities.
The E107 HOF cards are valuable as heck, and none of those are "one-of-one" cards.
The N167 HOF cards are valuable as heck, and none of those are "one-of-one" cards.
The 1904 Alleghany cards ARE "one-of-one"... so I would be curious to see what a nice HOF card from that set would sell for now.
In a nutshell, every collector wants to own something that NOBODY else owns... and the Alphas certainly fall into that category.