Yes, centering and registration matter quite a bit to me. The worse it is the better I like it!
Ok, probably not everyones thing, but I like them. Started when I got the Holtzman out of a pack. So far off center and from the edge of the sheet it's about 1/4 inch short. The 75 isn't factory, I was really disappointed when the uy I got it from confessed he'd cut a damaged sheet into nice condition blocks and "salvaged" a couple from the debris. Still interesting as a conversation piece.
I do also like really well centered and registered cards too, it's all the average ones that are a bit dull.
Steve B