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Gary B.In the comic book world, the #1 edition of almost any comic commands a premium, often very significantly higher than any other issues, with often the #1 being the only one of any real value at all. Since for the most part baseball card sets all come out at once (except in the high number phenomena), technically there should be no reason for a premium on a #1. If there is, it's due to as Steve described, kids putting cards in numerical order (I honestly can't remember if I ever did that as a kid - probably) and therefore the #1 getting the biggest hit, but otherwise I see no good reason why any #1 would be worth more than a #427, unless of course #1 was Mark McGwire and #427 was Marty Barrett.