This type of question has been asked for the past 20 years in this forum (and its predecessor). The answer is always exactly the same because people are predictable.
Not many will venture beyond the most commonly collected sets… so T206, Goudey, Cracker Jack, etc
Not many will venture beyond the most commonly collected players… so Ruth, Cobb, Gehrig, Joe Jackson, Wagner, etc
Put them together and you will have the answer to your question.