With 53 men on the active roster of each team, an opening day inclusive set of 32 teams would contain 1664 cards. Without short prints and five cards in a pack, there would be one Brady or Rodgers card in every 333 packs.
With injuries each week, an update set might be possible every two weeks during the season with highly coveted MRI Refractor inserts of your fallen heroes.
Sounds like a gold mine to me. And if you have never seen a refracted MRI, you are in for a treat.