Posted By:
barrysloateCliff Lee at 19-2 is approaching the best winning percentage for any pitcher with 20 wins, regardless of the team's record. I don't believe any pitcher ever won 20 games with two or fewer losses. Guidry at 25-3 and Grove at 31-4 are the all-time best.
Greg Maddux was 19-2 for the most wins with two losses.
Edited to correct an error.