It really depends on the collector; a miscut card affects the technical grade (either with or without a qualifier) since the centering or demensions are far from perfect.
But others, including myself, love collecting cards with interesting miscuts. The prices for these really seem to swing wildly... right now, they seem to be going for no more than a non-miscut card at the same grade (at least this was evidenced by my latest Sterling consignments).
For me a card with typical MC qualifier isn't going to get my attention. Partial names on top or bottom are easily found. If I find a card I like, I'll pay a premium for it... like I did for this Rossman:
